Famous autistic savants

Alonzo Clemons, American clay sculptor

Tony DeBlois, blind American musician

Leslie Lemke, blind American musician

Jonathan Lerman, American artist

Thristan Mendoza, Filipino marimba prodigy

Jerry Newport is an author, savant, and has Asperger's. His wife, Mary Newport, is also a savant on the autistic spectrum

Derek Paravicini, blind British musician

James Henry Pullen, gifted British carpenter

Matt Savage, U.S. autistic jazz prodigy

Henriett Seth-F., Hungarian autistic savant, poet, writer and artist

 

People with severe autism

Tito Mukhopadhyay, author, poet and philosopher

 

Fictional characters described by the
authors as being on the
autistic spectrum:

Boo Radley from To Kill a Mockingbird by Harper Lee (debated)

Albino from The Technopriests by Alejandro Jodorowsky and Zoran Janjetov

Lou Arrendale and his associates from The Speed of Dark by Elizabeth Moon.

Caleb Applewhite from the television show Desperate Housewives

Raymond Babbitt from the film Rain Man played by Dustin Hoffman 

Christopher John Francis Boone in the book The Curious Incident of the Dog in the Night-time by Mark Haddon

Kazan from the film Cube

Roy Cropper From Coronation Street

Jerry "Hands" Espenson from the television show Boston Legal

Lily Montgomery (Jackson Montgomery's daughter) on the television show All My Children.

Jade from Fahrenheit

Simon Lynch from the film Mercury Rising

Stone on General Hospital-Jagger's son. 

Dr. Kio Masada from C. S. Friedman's This Alien Shore is an autistic savant with a talent for computer science. The book also mentions his deceased wife, a musically gifted autistic savant, and includes Masada's musings on the nature of their relationship. Within the text, members of their culture refer to them as iru, but Friedman has confirmed that this term is meant to be analogous to autism.

Darryl McAllister from A Wizard Alone, part of Diane Duane's Young Wizards series. His autism gives him an unusual perspective of the world that in turn gives him unique abilities as a wizard.

Ellen Ripley from the film Alien: Resurrection, described as "emotionally autistic" after her resurrection.

Cody from the film Bless the Child.

Sheperd from the book By the Light of the Moon.

Arnie O' Conner from Dean Koontz's Frankenstien.

Seth Wyler from Stephen King's book The Regulators.

Charlie Godfrey from Betsy Byars' novel Summer of the Swans.

Reed Richards: Alicia Masters and Susan Storm speculated that Reed's social inadequecy and scientific aptitude were a result of Asperger's Syndrome in Fantastic Four: 1234 by Grant Morrison.

Protagonist Raam of the 2005 internationally-acclaimed Tamil film Raam (film).

J, a recurring character in the video game Final Fight.

Mayuko (Rie Tomosaka) in the 2000 dorama Kimi ga oshiete kureta koto

Teru (Fumiya Fujii) in the 2000 dorama Tenshi ga kieta machi

Theo on Days of Our Lives-Lexie and Abe's son. 

Natalie Flanagan from Gennifer Choldenko's 2004 youth novel Al Capone Does My Shirts

Marty Zellerbach from Robert Ludlum's novel, The Hades Factor

Legion (Marvel Comics)

Mozart and the Whale-
Film about a love story between two savants, Donald Morton and
Isabelle Sorenson, with Asperger's syndrome, a kind of autism

The Other Sister-
Film which doesn't mention autism, but character Daniel McMann is
definitely on spectrum and Carla Tate might be as well.

The Curious Incident of the Dog in the Night-time-
The story is written in the first-person perspective of Christopher
John Francis Boone, a 15-year-old autistic boy living in Swindon,
Wiltshire. Although Christopher's condition within the autism spectrum
is not stated explicitly within the novel, the summary on the book's
inside cover describes it as Asperger syndrome.